Pharmacoepidemiology Publications

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PharmacoEpidemiology Group (PEG) conducts research in the areas prescription drug utilization, epidemiological research methods, evaluation of drug policy and educational interventions, and drug safety and effectiveness. Selected journal articles and reports co-authored by PEG members are listed below. 

 

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Journal Articles

 

Authors Title Journal Bibliography Abstract Full text PDF
Morrow RL, Garland EJ, Wright JM, Maclure M, Taylor S, Dormuth CR Influence of relative age on diagnosis and treatment of attention-deficit/hyperactivity disorder in children CMAJ 2012 Apr 17;184(7): 755-62. Epub 2012 Mar 5 View Read Download
Garrison SR, Dormuth CR, Morrow RL, Carney GA, Khan KM Nocturnal Leg Cramps and Prescription Use That Precedes Them: A Sequence Symmetry Analysis Arch Intern Med 2012 Jan 22;172:120-126. Epub 2011 Dec 12 View    
Cadarette SM, Carney G, Baek D, Gunraj N, Paterson JM, Dormuth CR Osteoporosis medication prescribing in British Columbia and Ontario: impact of public drug coverage Osteoporos Int Epub: 2011 Sep 8 View Read  
Dormuth CR, Morrow RL, Carney G Trends in health care utilization in British Columbia following public coverage for tiotropium Value Health 2011 Jun;14(4):600-6. Epub 2011 May 25 View    
Patrick AR, Shrank WH, Glynn RJ, Solomon DH, Dormuth CR, Avorn J, Cadarette SM, Mogun H, Brookhart MA The association between statin use and outcomes potentially attributable to an unhealthy lifestyle in older adults Value Health 2011 Jun;14(4):513-20. Epub 2011 Apr 22 View    
Margulis AV, Choudhry NK, Dormuth CR, Schneeweiss S Variation in initiating secondary prevention after myocardial infarction by hospitals and physicians, 1997 through 2004 Pharmacoepidemiol Drug Saf 2011 Oct;20(10):1088-97. Epub 2011 Apr 28 View    
Polinski JM, Schneeweiss S, Maclure M, Marshall B, Ramsden S, Dormuth C Time series evaluation of an intervention to increase statin tablet splitting by general practitioners Clin Ther 2011 Feb;33(2):235-43 View Read  
Wiley-Exley E, Wang PS, Patrick AR, Dormuth C, Maclure M, Avorn J, Canning CF, Schneeweiss S Impact of drug cost sharing on service use and adverse clinical outcomes in elderly receiving antidepressants J Ment Health Policy Econ 2010Mar;13(1):37-44 View    
Schneeweiss S, Patrick AR, Solomon DH, Mehta J, Dormuth C, Miller M, Lee JC, Wang PS Variation in the risk of suicide attempts and completed suicides by antidepressant agent in adults: a propensity score-adjusted analysis of 9 years' data Arch Gen Psychiatry 2010May;67(5):497-506. View    
Schneeweiss S, Patrick AR, Solomon DH, Dormuth CR, Miller M, Mehta J, Lee JC, Wang PS Comparative safety of antidepressant agents for children and adolescents regarding suicidal acts Pediatrics 2010 May;125(5):876-88 Epub 2010 Apr 12 View    
Morrow RL, Carney G, Wright JM, Bassett K, Sutherland J, Dormuth CR Impact of rosiglitazone meta-analysis on use of glucose-lowering medications Open Med 2010;4(1): E50-9 View Read Download
Brookhart MA, Patrick AR, Shrank WH, Dormuth CR Validating studies of adherence through the use of control outcomes and exposures Am J Hypertens 2010 Feb;23(2):110    
Johnson ML, Crown W, Martin BC, Dormuth CR, Siebert U Good research practices for comparative effectiveness research: analytic methods to improve causal inference from nonrandomized studies of treatment effects using secondary data sources: the ISPOR good research practices for retrospective database analysis task force report-part III Value Health 2009 Sep 29 View    
Dormuth CR, Carney G, Carleton B, Bassett K, Wright JM Thiazolidinediones and fractures in men and women Arch Intern Med 2009 Aug 10;169(15):1395-402 View    
Dormuth CR, Maclure M, Carney G, Schneeweiss S, Bassett K, Wright JM Rosiglitazone and myocardial infarction in patients previously prescribed metformin PLoS One 2009 Jun 27;4(6):e6080 View   Download
Dormuth CR, Neumann P, Maclure M, Glynn RJ, Schneeweiss S Effects of prescription coinsurance and income-based deductibles on net health plan spending for older users of in-haled medications Med Care 2009May;47(5):508-16 View    
Dormuth CR, Patrick AR, Shrank WH, Wright JM, Glynn RJ, Sutherland J, Brookhart MA Statin Adherence and risk of accidents: a cautionary tale Circulation 2009 Apr21;119(15):2051-7 Epub 2009 Apr 6 View Read Download
Dormuth CR, Schneeweiss S, Brookhart AM, Carney G, Bassett K, Adams S, Wright JM Factors related to splitting statin tablets: A population-based analysis in British Columbia Open Medicine 2008;2(3):E5-13 View Read Download
Dormuth CR, Maclure M, Glynn RJ, Neumann P, Brookhart AM, Schneeweiss S Emergency hospital admissions after income-based deductibles and prescription copayments in older users of inhaled medications Clin Ther 2008;30P1:1038-1050 View    
Wang PS, Patrick AR, Dormuth CR, Avorn J, Maclure M, Canning CF, Schneeweiss S The impact of cost sharing on antidepressant use among older adults in british columbia Psychiatr Serv 2008 Apr;59(4):377-83 View Read Download
Brookhart MA, Rassen JA, Wang PS, Dormuth C, Mogun H, Schneeweiss S Evaluating the validity of an instrumental variable study of neuroleptics: can between- physician differences in prescribing patterns be used to estimate treatment effects? Med Care 2007 Oct;45(10 Supl 2):S116-22 View    
Schneeweiss S, Patrick AR, Maclure M, Dormuth CR, Glynn RJ Adherence to beta-blocker therapy under drug cost-sharing in patients with and without acute myocardial infarction Am J Manag Care 2007 Aug;13(8):445-52 View Read Download
Brookhart MA, Patrick AR, Dormuth C, Avorn J, Shrank W, Cadarette SM, Solomon DH Adherence to Lipid-lowering Therapy and the Use of Preventive Health Services: An Investigation of the Healthy User Effect Am J Epidemiol 2007 May 15; [Epub ahead of print] View Read Download
Brookhart MA, Patrick AR, Schneeweiss S, Avorn J, Dormuth C, Shrank W, van Wijk L, Cadarette SM, Canning CF, Solomon DH Physician follow-up and provider continuity are associated with long-term medication adherence: a study of the dynamics of statin use Arch Intern Med 2007 Apr 23;167(8):847-52 View Read Download
Schneeweiss S, Patrick AR, Maclure M, Dormuth CR, Glynn RJ Adherence to statin therapy under drug cost sharing in patients with and without acute myocardial infarction: a population-based natural experiment Circulation 2007 Apr 24;115(16):2128-35 Epub 2007 Apr 9 View Read Download
Schneeweiss S, Setoguchi S, Brookhart A, Dormuth C, Wang PS Risk of death associated with the use of conventional versus atypical antipsychotic drugs among elderly patients CMAJ 2007 Feb 27;176(5):627-32 View Read Download
Paterson JM, Carney G, Anderson GM, Bassett K, Naglie G, Laupacis A; BC-Ontario Pharmacosurveillance for Decision-making Collaborative. Case selection for statins was similar in two Canadian provinces: BC and Ontario. J Clin Epidemiol 2007 Jan;60(1):73-8. Epub 2006 Sep 7 View    
Dormuth CR, Glynn RJ, Neumann P, Maclure M, Brookhart AM, Schneeweiss S Impact of two sequential drug cost-sharing policies on the use of inhaled medications in older patients with COPD or asthma Clin Ther 2006 Jun;28(6):964-78 View    
Setoguchi S, Solomon DH, Weinblatt ME, Katz JN, Avorn J, Glynn RJ, Cook EF, Carney G, Schneeweiss S. Tumor necrosis factor alpha antagonist use and cancer in patients with rheumatoid arthritis. Arthritis Rheum 2006 Sep;54(9):2757-64. Erratum in: Arthritis Rheum. 2006 Oct;54(10):3134.  View Read Download
Maclure M, Nguyen A, Carney G, Dormuth C, Roelants H, Ho K, Schneeweiss S Measuring prescribing improvements in pragmatic trials of education tools for general practitioners Basic Clin Pharmacol Toxicol 2006; 98(3): 243-52 View    
Schneeweiss S, Maclure M, Dormuth C, Glynn RJ, Canning C, Avorn J A therapeutic substitution policy for proton pump inhibitors: clinical and economic consequences Clin Pharmacol Ther 2006; 79(4): 379-88 View    
Dormuth CR, Burnett S, Schneeweiss S Predicting drug plan expenditure while planning reimbursement changes using policy simulation Pharmacoeconomics 2005 Sep View    
Dormuth CR, Maclure M, Bassett K, Jauca C, Whiteside C, Wright JM Effect of periodic letters on evidence-based drug therapy on prescribing behaviour: a randomized trial CMAJ 2004 Oct;171(9):1057-61 View Read Download
Herbert CP, Wright JM, Maclure M, Wakefield J, Dormuth C, Brett-MacLean P, Legare J, Premi J Better Prescribing Project: a randomized controlled trial of the impact of case-based educational modules and personal prescribing feedback on prescribing for hypertension in primary care Fam Pract 2004 Oct;21(5):575-81 View Read Download
Schneeweiss S, Dormuth C, Grootendorst P, Soumerai SB, Maclure M Net health plan savings from reference pricing for angiotensin-converting enzyme inhibitors in elderly British Columbia residents Med Care 2004 Jul;42(7):653-60 View    
Schneeweiss S, Soumerai SB, Maclure M, Dormuth C, Walker AM, Glynn RJ Clinical and economic consequences of reference pricing for dihydropyridine calcium channel blockers Clin Pharmacol Ther 2003 Oct;74(4):388-400 View    
Wakefield J, Herbert CP, Maclure M, Dormuth C, Wright JM, Legare J, Brett-MacLean P, Premi J Commitment to change statements can predict actual change in practice J Contin Educ Health Prof 2003 Spring;23(2):81-93  View    
Schneeweiss S, Maclure M, Dormuth C On the evaluation of drug policy changes with longitudinal claims data: Concepts of income-based deductibles and issues related to causal inference Disease Management & Health Outcomes 2002;10:763-769 View    
Schneeweiss S, Maclure M, Dormuth C, Avorn J Pharmaceutical cost containment with reference-based pricing: time for refinements CMAJ 2002 Nov 26;167(11):1250-1 No abstract available   Read Download
Schneeweiss S, Soumerai SB, Glynn RJ, Maclure M, Dormuth C, Walker AM Impact of reference-based pricing for angiotensin-converting enzyme inhibitors on drug utilization CMAJ 2002 Mar 19;166(6):737-45 View Read Download
Schneeweiss S, Walker AM, Glynn RJ, Maclure M, Dormuth C, Soumerai SB Outcomes of reference pricing for angiotensin-converting-enzyme inhibitors N Engl J Med 2002 Mar 14;346(11):822-9 View Read Download
Maclure M, Dormuth C, Naumann T, McCormack J, Rangno R, Whiteside C, Wright JM Influences of educational interventions and adverse news about calcium-channel blockers on first-line prescribing of antihypertensive drugs to elderly people in British Columbia Lancet 1998 19;352(9132):943-8 View    

Reports

Date Title PDF
Mar 2008 Pharmaceutical Expenditure in BC Top 20 Chemicals by Drug Cost (2007)
PDF   (112 KB)
Feb 2008 British Columbia Statin Costs and Utilization, 2004-2007
PDF   (48 KB)
Jun 2005 Incorporating Pharmacosurveillance in Provincial Drug Formulary Decision-Making.
PDF   (436 KB)
Nov 2003 What Effects do Provincial Drug Plan Coverage Policies for New Drugs have on Patterns of Use and Cost.
PDF   (1.1 MB)